NOW Foods CurcuBrain™ 400mg is a powerful free radical neutraliser that is known to support balanced immune function, but is also known to have poor bioavailability.* NOW® CurcuBrain™ features Longvida® Optimized Curcumin, which in studies exhibits up to 65 times the bioavailability of free curcuminoids compared with generic curcumin.* Longvida® is absorbed by the GI tract and delivered to the rest of the body as free curcumin, the active form in the body.* Longvida® is shown to penetrate the blood-brain barrier for the support of healthy neuronal tissues.